Acireductone dioxygenase (ADI1)

About Acireductone dioxygenase

Acireductone dioxygenase (ADI1) is a protein from Homo sapiens identified by UniProt accession Q9BV57, 179 residues long. MolForge cross-references it against 0 known binders and 78 disease associations.

Target properties

Protein name	Acireductone dioxygenase
UniProt accession	Q9BV57
Gene	ADI1
Organism	Homo sapiens
Length	179 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (78)

Diseases linked to this target (Open Targets).

neoplasm · score 0.08
hepatocellular carcinoma · score 0.08
malaria · score 0.05
cancer · score 0.04
infect · score 0.03
infection · score 0.03
exstrophy-epispadias complex · score 0.03
hepatitis C virus infection · score 0.02
Rheumatoid arthritis · score 0.02
neuropathy · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BV57-F1	alphafold	PREDICTED	96.61	—

Amino-acid sequence (179 residues)

MVQAWYMDDA PGDPRQPHRP DPGRPVGLEQ LRRLGVLYWK LDADKYENDP ELEKIRRERN YSWMDIITIC KDKLPNYEEK IKMFYEEHLH LDDEIRYILD GSGYFDVRDK EDQWIRIFME KGDMVTLPAG IYHRFTVDEK NYTKAMRLFV GEPVWTAYNR PADHFEARGQ YVKFLAQTA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards