E3 ubiquitin-protein ligase RNF126 (RNF126)

About E3 ubiquitin-protein ligase RNF126

E3 ubiquitin-protein ligase RNF126 (RNF126) is a protein from Homo sapiens identified by UniProt accession Q9BV68, 311 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.

Target properties

Protein name	E3 ubiquitin-protein ligase RNF126
UniProt accession	Q9BV68
Gene	RNF126
Organism	Homo sapiens
Length	311 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BV68-F1	alphafold	PREDICTED	61.44	—

Amino-acid sequence (311 residues)

MAEASPHPGR YFCHCCSVEI VPRLPDYICP RCESGFIEEL PEETRSTENG SAPSTAPTDQ SRPPLEHVDQ HLFTLPQGYG QFAFGIFDDS FEIPTFPPGA QADDGRDPES RRERDHPSRH RYGARQPRAR LTTRRATGRH EGVPTLEGII QQLVNGIITP ATIPSLGPWG VLHSNPMDYA WGANGLDAII TQLLNQFENT GPPPADKEKI QALPTVPVTE EHVGSGLECP VCKDDYALGE RVRQLPCNHL FHDGCIVPWL EQHDSCPVCR KSLTGQNTAT NPPGLTGVSF SSSSSSSSSS SPSNENATSN S

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards