About ER membrane protein complex subunit 6
ER membrane protein complex subunit 6 (EMC6) is a protein
from Homo sapiens identified by UniProt accession
Q9BV81, 110 residues long.
MolForge cross-references it against 0 known binders and
54 disease associations.
Target properties
| Protein name | ER membrane protein complex subunit 6 |
|---|
| UniProt accession | Q9BV81 |
|---|
| Gene | EMC6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 110 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (54)
Diseases linked to this target (Open Targets).
- cancer · score 0.08
- lung adenocarcinoma · score 0.08
- glioblastoma multiforme · score 0.07
- pachyonychia congenita · score 0.07
- neoplasm · score 0.06
- primary familial polycythemia due to EPO receptor mutation · score 0.05
- hemolytic anemia due to diphosphoglycerate mutase deficiency · score 0.04
- X-linked sideroblastic anemia 1 · score 0.04
- erythrocytosis, familial, 3 · score 0.04
- erythrocytosis, familial, 6 · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BV81-F1 | alphafold | PREDICTED | 82.63 | — |
Amino-acid sequence (110 residues)
MAAVVAKREG PPFISEAAVR GNAAVLDYCR TSVSALSGAT AGILGLTGLY GFIFYLLASV LLSLLLILKA GRRWNKYFKS RRPLFTGGLI GGLFTYVLFW TFLYGMVHVY
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