N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1)

About N-terminal Xaa-Pro-Lys N-methyltransferase 1

N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) is a protein from Homo sapiens identified by UniProt accession Q9BV86, 223 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.

Target properties

Protein name	N-terminal Xaa-Pro-Lys N-methyltransferase 1
UniProt accession	Q9BV86
Gene	NTMT1
Organism	Homo sapiens
Length	223 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BV86-F1	alphafold	PREDICTED	97.54	—

Amino-acid sequence (223 residues)

MTSEVIEDEK QFYSKAKTYW KQIPPTVDGM LGGYGHISSI DINSSRKFLQ RFLREGPNKT GTSCALDCGA GIGRITKRLL LPLFREVDMV DITEDFLVQA KTYLGEEGKR VRNYFCCGLQ DFTPEPDSYD VIWIQWVIGH LTDQHLAEFL RRCKGSLRPN GIIVIKDNMA QEGVILDDVD SSVCRDLDVV RRIICSAGLS LLAEERQENL PDEIYHVYSF ALR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards