Leucine-rich repeat-containing protein 61 (LRRC61)

About Leucine-rich repeat-containing protein 61

Leucine-rich repeat-containing protein 61 (LRRC61) is a protein from Homo sapiens identified by UniProt accession Q9BV99, 259 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

Target properties

Protein name	Leucine-rich repeat-containing protein 61
UniProt accession	Q9BV99
Gene	LRRC61
Organism	Homo sapiens
Length	259 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (15)

Diseases linked to this target (Open Targets).

chemerin measurement · score 0.33
protein measurement · score 0.22
platelet count · score 0.20
self reported educational attainment · score 0.19
retinoic acid receptor responder protein 2 measurement · score 0.17
appendicular lean mass · score 0.15
blood protein measurement · score 0.15
visual perception measurement · score 0.09
systolic blood pressure · score 0.05
adolescent idiopathic scoliosis · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BV99-F1	alphafold	PREDICTED	84.46	—

Amino-acid sequence (259 residues)

MDPPAEKPGE AGGLQITPQL LKSRTGEFSL ESILLLKLRG LGLADLGCLG ECLGLEWLDL SGNALTHLGP LASLRQLAVL NVSNNRLTGL EPLATCENLQ SLNAAGNLLA TPGQLQCLAG LPCLEYLRLR DPLARLSNPL CANPSYWAAV RELLPGLKVI DGERVIGRGS EFYQLCRDLD SSLRPSSSPG PRATEAQPWV EPGYWESWPS RSSSILEEAC RQFQDTLQEC WDLDRQASDS LAQAEQVLSS AGPTSSFVF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards