Sister chromatid cohesion protein DCC1 (DSCC1)

About Sister chromatid cohesion protein DCC1

Sister chromatid cohesion protein DCC1 (DSCC1) is a protein from Homo sapiens identified by UniProt accession Q9BVC3, 393 residues long. MolForge cross-references it against 0 known binders and 61 disease associations.

Target properties

Protein name	Sister chromatid cohesion protein DCC1
UniProt accession	Q9BVC3
Gene	DSCC1
Organism	Homo sapiens
Length	393 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (61)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.43
body height · score 0.18
mean corpuscular volume · score 0.13
Myocardial Ischemia · score 0.10
platelet crit · score 0.10
lung adenocarcinoma · score 0.09
mean reticulocyte volume · score 0.09
red blood cell density measurement · score 0.09
hepatocellular carcinoma · score 0.08
BMI-adjusted hip circumference · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BVC3-F1	alphafold	PREDICTED	91.59	—

Amino-acid sequence (393 residues)

MKRTRDEVDA TLQIAKLNAA ELLPAVHCLG FGPGASGAAA GDFCLLELEP TLCQQLEDGH SLVIRGDKDE QAVLCSKDKT YDLKIADTSN MLLFIPGCKT PDQLKKEDSH CNIIHTEIFG FSNNYWELRR RRPKLKKLKK LLMENPYEGP DSQKEKDSNS SKYTTEDLLD QIQASEEEIM TQLQVLNACK IGGYWRILEF DYEMKLLNHV TQLVDSESWS FGKVPLNTCL QELGPLEPEE MIEHCLKCYG KKYVDEGEVY FELDADKICR AAARMLLQNA VKFNLAEFQE VWQQSVPEGM VTSLDQLKGL ALVDRHSRPE IIFLLKVDDL PEDNQERFNS LFSLREKWTE EDIAPYIQDL CGEKQTIGAL LTKYSHSSMQ NGVKVYNSRR PIS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards