Dual specificity protein phosphatase 23 (DUSP23)

About Dual specificity protein phosphatase 23

Dual specificity protein phosphatase 23 (DUSP23) is a protein from Homo sapiens identified by UniProt accession Q9BVJ7, 150 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

Target properties

Protein name	Dual specificity protein phosphatase 23
UniProt accession	Q9BVJ7
Gene	DUSP23
Organism	Homo sapiens
Length	150 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (15)

Diseases linked to this target (Open Targets).

C-reactive protein measurement · score 0.33
neurodegenerative disease · score 0.27
neurofibrillary tangles measurement · score 0.20
acute myeloid leukemia · score 0.07
protein measurement · score 0.04
bacterial disease · score 0.03
Systemic lupus erythematosus · score 0.02
cancer · score 0.02
tuberculosis · score 0.01
Crohn's disease · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BVJ7-F1	alphafold	PREDICTED	97.53	—

Amino-acid sequence (150 residues)

MGVQPPNFSW VLPGRLAGLA LPRLPAHYQF LLDLGVRHLV SLTERGPPHS DSCPGLTLHR LRIPDFCPPA PDQIDRFVQI VDEANARGEA VGVHCALGFG RTGTMLACYL VKERGLAAGD AIAEIRRLRP GSIETYEQEK AVFQFYQRTK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards