About Protein adenylyltransferase SelO, mitochondrial
Protein adenylyltransferase SelO, mitochondrial (SELENOO) is a protein
from Homo sapiens identified by UniProt accession
Q9BVL4, 669 residues long.
MolForge cross-references it against 0 known binders and
36 disease associations.
Target properties
| Protein name | Protein adenylyltransferase SelO, mitochondrial |
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| UniProt accession | Q9BVL4 |
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| Gene | SELENOO |
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| Organism | Homo sapiens |
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| Length | 669 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (36)
Diseases linked to this target (Open Targets).
- brain volume measurement · score 0.24
- platelet count · score 0.20
- platelet crit · score 0.16
- eosinophil count · score 0.16
- mean platelet volume · score 0.15
- liver fibrosis measurement · score 0.14
- mitochondrial DNA measurement · score 0.11
- eosinophil percentage of leukocytes · score 0.10
- unipolar depression · score 0.10
- bipolar disorder · score 0.10
Amino-acid sequence (669 residues)
MAVYRAALGA SLAAARLLPL GRCSPSPAPR STLSGAAMEP APRWLAGLRF DNRALRALPV EAPPPGPEGA PSAPRPVPGA CFTRVQPTPL RQPRLVALSE PALALLGLGA PPAREAEAEA ALFFSGNALL PGAEPAAHCY CGHQFGQFAG QLGDGAAMYL GEVCTATGER WELQLKGAGP TPFSRQADGR KVLRSSIREF LCSEAMFHLG VPTTRAGACV TSESTVVRDV FYDGNPKYEQ CTVVLRVAST FIRFGSFEIF KSADEHTGRA GPSVGRNDIR VQLLDYVISS FYPEIQAAHA SDSVQRNAAF FREVTRRTAR MVAEWQCVGF CHGVLNTDNM SILGLTIDYG PFGFLDRYDP DHVCNASDNT GRYAYSKQPE VCRWNLRKLA EALQPELPLE LGEAILAEEF DAEFQRHYLQ KMRRKLGLVQ VELEEDGALV SKLLETMHLT GADFTNTFYL LSSFPVELES PGLAEFLARL MEQCASLEEL RLAFRPQMDP RQLSMMLMLA QSNPQLFALM GTRAGIAREL ERVEQQSRLE QLSAAELQSR NQGHWADWLQ AYRARLDKDL EGAGDAAAWQ AEHVRVMHAN NPKYVLRNYI AQNAIEAAER GDFSEVRRVL KLLETPYHCE AGAATDAEAT EADGADGRQR SYSSKPPLWA AELCVTUSS
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