About Fibronectin type III domain-containing protein 11
Fibronectin type III domain-containing protein 11 (FNDC11) is a protein
from Homo sapiens identified by UniProt accession
Q9BVV2, 318 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Fibronectin type III domain-containing protein 11 |
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| UniProt accession | Q9BVV2 |
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| Gene | FNDC11 |
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| Organism | Homo sapiens |
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| Length | 318 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (8)
Diseases linked to this target (Open Targets).
- joint disease · score 0.11
- Red cell distribution width · score 0.04
- bone density · score 0.04
- urate measurement · score 0.04
- skin cancer · score 0.02
- non-melanoma skin carcinoma · score 0.02
- benign neoplasm · score 0.02
- telomere length · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BVV2-F1 | alphafold | PREDICTED | 82.04 | — |
Amino-acid sequence (318 residues)
MSTHVAGLGL DKMKLGNPQS FLDQEEADDQ QLLEPEAWKT YTERRNALRE FLTSDLSPHL LKRHHARMQL LRKCSYYIEV LPKHLALGDQ NPLVLPSALF QLIDPWKFQR MKKVGTAQTK IQLLLLGDLL EQLDHGRAEL DALLRSPDPR PFLADWALVE RRLADVSAVM DSFLTMMVPG RLHVKHRLVS DVSATKIPHI WLMLSTKMPV VFDRKASAAH QDWARLRWFV TIQPATSEQY ELRFRLLDPR TQQECAQCGV IPVAACTFDV RNLLPNRSYK FTIKRAETST LVYEPWRDSL TLHTKPEPLE GPALSHSV
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