About Mitochondrial import inner membrane translocase subunit Tim21
Mitochondrial import inner membrane translocase subunit Tim21 (TIMM21) is a protein
from Homo sapiens identified by UniProt accession
Q9BVV7, 248 residues long.
MolForge cross-references it against 0 known binders and
14 disease associations.
Target properties
| Protein name | Mitochondrial import inner membrane translocase subunit Tim21 |
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| UniProt accession | Q9BVV7 |
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| Gene | TIMM21 |
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| Organism | Homo sapiens |
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| Length | 248 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (14)
Diseases linked to this target (Open Targets).
- testosterone measurement · score 0.14
- sleep measurement · score 0.14
- longevity · score 0.08
- 17-hydroxyprogesterone measurement · score 0.08
- PHF-tau measurement · score 0.07
- metabolite measurement · score 0.07
- systemic juvenile idiopathic arthritis · score 0.01
- neoplasm · score 0.00
- acute lymphoblastic leukemia · score 0.00
- mitochondrial disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BVV7-F1 | alphafold | PREDICTED | 73.01 | — |
Amino-acid sequence (248 residues)
MICTFLRAVQ YTEKLHRSSA KRLLLPYIVL NKACLKTEPS LRCGLQYQKK TLRPRCILGV TQKTIWTQGP SPRKAKEDGS KQVSVHRSQR GGTAVPTSQK VKEAGRDFTY LIVVLFGISI TGGLFYTIFK ELFSSSSPSK IYGRALEKCR SHPEVIGVFG ESVKGYGEVT RRGRRQHVRF TEYVKDGLKH TCVKFYIEGS EPGKQGTVYA QVKENPGSGE YDFRYIFVEI ESYPRRTIII EDNRSQDD
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