About Kinesin-like protein KIFC1
Kinesin-like protein KIFC1 (KIFC1) is a protein
from Homo sapiens identified by UniProt accession
Q9BW19, 673 residues long.
MolForge cross-references it against 0 known binders and
107 disease associations.
Target properties
| Protein name | Kinesin-like protein KIFC1 |
|---|
| UniProt accession | Q9BW19 |
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| Gene | KIFC1 |
|---|
| Organism | Homo sapiens |
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| Length | 673 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (107)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.18
- esophageal cancer · score 0.15
- hepatocellular carcinoma · score 0.12
- neoplasm · score 0.11
- cancer · score 0.10
- lymphocyte count · score 0.10
- triple-negative breast cancer · score 0.10
- breast cancer · score 0.10
- attention deficit hyperactivity disorder · score 0.08
- glioblastoma multiforme · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BW19-F1 | alphafold | PREDICTED | 77.60 | — |
Amino-acid sequence (673 residues)
MDPQRSPLLE VKGNIELKRP LIKAPSQLPL SGSRLKRRPD QMEDGLEPEK KRTRGLGATT KITTSHPRVP SLTTVPQTQG QTTAQKVSKK TGPRCSTAIA TGLKNQKPVP AVPVQKSGTS GVPPMAGGKK PSKRPAWDLK GQLCDLNAEL KRCRERTQTL DQENQQLQDQ LRDAQQQVKA LGTERTTLEG HLAKVQAQAE QGQQELKNLR ACVLELEERL STQEGLVQEL QKKQVELQEE RRGLMSQLEE KERRLQTSEA ALSSSQAEVA SLRQETVAQA ALLTEREERL HGLEMERRRL HNQLQELKGN IRVFCRVRPV LPGEPTPPPG LLLFPSGPGG PSDPPTRLSL SRSDERRGTL SGAPAPPTRH DFSFDRVFPP GSGQDEVFEE IAMLVQSALD GYPVCIFAYG QTGSGKTFTM EGGPGGDPQL EGLIPRALRH LFSVAQELSG QGWTYSFVAS YVEIYNETVR DLLATGTRKG QGGECEIRRA GPGSEELTVT NARYVPVSCE KEVDALLHLA RQNRAVARTA QNERSSRSHS VFQLQISGEH SSRGLQCGAP LSLVDLAGSE RLDPGLALGP GERERLRETQ AINSSLSTLG LVIMALSNKE SHVPYRNSKL TYLLQNSLGG SAKMLMFVNI SPLEENVSES LNSLRFASKV NQCVIGTAQA NRK
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