Tubulin polymerization-promoting protein family…

About Tubulin polymerization-promoting protein family member 3

Tubulin polymerization-promoting protein family member 3 (TPPP3) is a protein from Homo sapiens identified by UniProt accession Q9BW30, 176 residues long. MolForge cross-references it against 0 known binders and 155 disease associations.

Target properties

Protein name	Tubulin polymerization-promoting protein family member 3
UniProt accession	Q9BW30
Gene	TPPP3
Organism	Homo sapiens
Length	176 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (155)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.23
erythrocyte count · score 0.10
blood protein measurement · score 0.09
neoplasm · score 0.08
non-small cell lung carcinoma · score 0.08
mean corpuscular volume · score 0.08
BMI-adjusted waist circumference · score 0.08
glioblastoma · score 0.07
BMI-adjusted waist-hip ratio · score 0.07
melanoma · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BW30-F1	alphafold	PREDICTED	84.06	—

Amino-acid sequence (176 residues)

MAASTDMAGL EESFRKFAIH GDPKASGQEM NGKNWAKLCK DCKVADGKSV TGTDVDIVFS KVKGKSARVI NYEEFKKALE ELATKRFKGK SKEEAFDAIC QLVAGKEPAN VGVTKAKTGG AVDRLTDTSR YTGSHKERFD ESGKGKGIAG RQDILDDSGY VSAYKNAGTY DAKVKK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Tubulin polymerization-promoting protein family member 3 (TPPP3)