DET1- and DDB1-associated protein 1 (DDA1)

About DET1- and DDB1-associated protein 1

DET1- and DDB1-associated protein 1 (DDA1) is a protein from Homo sapiens identified by UniProt accession Q9BW61, 102 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

Target properties

Protein name	DET1- and DDB1-associated protein 1
UniProt accession	Q9BW61
Gene	DDA1
Organism	Homo sapiens
Length	102 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (20)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.37
neoplasm · score 0.09
low density lipoprotein cholesterol measurement · score 0.07
HbA1c measurement · score 0.02
hematocrit · score 0.02
breast carcinoma · score 0.02
ovarian carcinoma · score 0.02
cancer · score 0.02
acute myeloid leukemia · score 0.01
Plasmodium falciparum malaria · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BW61-F1	alphafold	PREDICTED	66.34	—

Amino-acid sequence (102 residues)

MADFLKGLPV YNKSNFSRFH ADSVCKASNR RPSVYLPTRE YPSEQIIVTE KTNILLRYLH QQWDKKNAAK KRDQEQVELE GESSAPPRKV ARTDSPDMHE DT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards