About Katanin p60 ATPase-containing subunit A-like 1
Katanin p60 ATPase-containing subunit A-like 1 (KATNAL1) is a protein
from Homo sapiens identified by UniProt accession
Q9BW62, 490 residues long.
MolForge cross-references it against 0 known binders and
178 disease associations.
Target properties
| Protein name | Katanin p60 ATPase-containing subunit A-like 1 |
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| UniProt accession | Q9BW62 |
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| Gene | KATNAL1 |
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| Organism | Homo sapiens |
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| Length | 490 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (178)
Diseases linked to this target (Open Targets).
- balding measurement · score 0.39
- hair shape measurement · score 0.32
- urate measurement · score 0.31
- bone density · score 0.31
- Abnormality of refraction · score 0.29
- age at first facial hair · score 0.23
- androgenetic alopecia · score 0.22
- mean corpuscular volume · score 0.18
- mean corpuscular hemoglobin concentration · score 0.17
- retinal vein occlusion · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BW62-F1 | alphafold | PREDICTED | 76.53 | — |
Amino-acid sequence (490 residues)
MNLAEICDNA KKGREYALLG NYDSSMVYYQ GVMQQIQRHC QSVRDPAIKG KWQQVRQELL EEYEQVKSIV STLESFKIDK PPDFPVSCQD EPFRDPAVWP PPVPAEHRAP PQIRRPNREV RPLRKEMAGV GARGPVGRAH PISKSEKPST SRDKDYRARG RDDKGRKNMQ DGASDGEMPK FDGAGYDKDL VEALERDIVS RNPSIHWDDI ADLEEAKKLL REAVVLPMWM PDFFKGIRRP WKGVLMVGPP GTGKTMLAKA VATECGTTFF NVSSSTLTSK YRGESEKLVR LLFEMARFYA PTTIFIDEID SICSRRGTSD EHEASRRVKS ELLIQMDGVG GALENDDPSK MVMVLAATNF PWDIDEALRR RLEKRIYIPL PTAKGRAELL KINLREVELD PDIQLEDIAE KIEGYSGADI TNVCRDASLM AMRRRINGLS PEEIRALSKE ELQMPVTKGD FELALKKIAK SVSAADLEKY EKWMVEFGSA
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