About Cyclin-dependent kinase 2-interacting protein
Cyclin-dependent kinase 2-interacting protein (CINP) is a protein
from Homo sapiens identified by UniProt accession
Q9BW66, 212 residues long.
MolForge cross-references it against 0 known binders and
35 disease associations.
Target properties
| Protein name | Cyclin-dependent kinase 2-interacting protein |
|---|
| UniProt accession | Q9BW66 |
|---|
| Gene | CINP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 212 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (35)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- Microcephaly · score 0.27
- Seizure · score 0.27
- Intellectual disability · score 0.27
- inosine-5'-monophosphate dehydrogenase 2 measurement · score 0.13
- hereditary spastic paraplegia · score 0.12
- hemoglobin measurement · score 0.10
- mean platelet volume · score 0.09
- MODY · score 0.06
- platelet count · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BW66-F1 | alphafold | PREDICTED | 87.74 | — |
Amino-acid sequence (212 residues)
MEAKTLGTVT PRKPVLSVSA RKIKDNAADW HNLILKWETL NDAGFTTANN IANLKISLLN KDKIELDSSS PASKENEEKV CLEYNEELEK LCEELQATLD GLTKIQVKME KLSSTTKGIC ELENYHYGEE SKRPPLFHTW PTTHFYEVSH KLLEMYRKEL LLKRTVAKEL AHTGDPDLTL SYLSMWLHQP YVESDSRLHL ESMLLETGHR AL
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