HIRA-interacting protein 3 (HIRIP3)

About HIRA-interacting protein 3

HIRA-interacting protein 3 (HIRIP3) is a protein from Homo sapiens identified by UniProt accession Q9BW71, 556 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	HIRA-interacting protein 3
UniProt accession	Q9BW71
Gene	HIRIP3
Organism	Homo sapiens
Length	556 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.48
body mass index · score 0.11
body weight · score 0.05
waist circumference · score 0.05
high density lipoprotein cholesterol measurement · score 0.05
lean body mass · score 0.04
feeling nervous measurement · score 0.03
smoking behavior · score 0.03
reticulocyte measurement · score 0.03
fat body mass · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BW71-F1	alphafold	PREDICTED	59.49	—

Amino-acid sequence (556 residues)

MAREKEMQEF TRSFFRGRPD LSTLTHSIVR RRYLAHSGRS HLEPEEKQAL KRLVEEELLK MQVDEAASRE DKLDLTKKGK RPPTPCSDPE RKRFRFNSES ESGSEASSPD YFGPPAKNGV AAEVSPAKEE NPRRASKAVE ESSDEERQRD LPAQRGEESS EEEEKGYKGK TRKKPVVKKQ APGKASVSRK QAREESEESE AEPVQRTAKK VEGNKGTKSL KESEQESEEE ILAQKKEQRE EEVEEEEKEE DEEKGDWKPR TRSNGRRKSA REERSCKQKS QAKRLLGDSD SEEEQKEAAS SGDDSGRDRE PPVQRKSEDR TQLKGGKRLS GSSEDEEDSG KGEPTAKGSR KMARLGSTSG EESDLEREVS DSEAGGGPQG ERKNRSSKKS SRKGRTRSSS SSSDGSPEAK GGKAGSGRRG EDHPAVMRLK RYIRACGAHR NYKKLLGSCC SHKERLSILR AELEALGMKG TPSLGKCRAL KEQREEAAEV ASLDVANIIS GSGRPRRRTA WNPLGEAAPP GELYRRTLDS DEERPRPAPP DWSHMRGIIS SDGESN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards