About Coiled-coil domain-containing protein 106
Coiled-coil domain-containing protein 106 (CCDC106) is a protein
from Homo sapiens identified by UniProt accession
Q9BWC9, 280 residues long.
MolForge cross-references it against 0 known binders and
17 disease associations.
Target properties
| Protein name | Coiled-coil domain-containing protein 106 |
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| UniProt accession | Q9BWC9 |
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| Gene | CCDC106 |
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| Organism | Homo sapiens |
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| Length | 280 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
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Disease associations (17)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.20
- ovarian cancer · score 0.07
- high density lipoprotein cholesterol measurement · score 0.05
- non-small cell lung carcinoma · score 0.05
- cancer · score 0.04
- hypouricemia, renal, 2 · score 0.03
- hypermetabolism due to uncoupled mitochondrial oxidative phosphorylation 2 · score 0.03
- neoplasm · score 0.02
- cervical carcinoma · score 0.01
- lymph node metastatic carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BWC9-F1 | alphafold | PREDICTED | 72.76 | — |
Amino-acid sequence (280 residues)
MNDRSSRRRT MKDDETFEIS IPFDEAPHLD PQIFYSLSPS RRNFEEPPEA ASSALALMNS VKTQLHMALE RNSWLQKRIE DLEEERDFLR CQLDKFISSA RMEAEDHCRM KPGPRRMEGD SRGGAGGEAS DPESAASSLS GASEEGSASE RRRQKQKGGA SRRRFGKPKA RERQRVKDAD GVLCRYKKIL GTFQKLKSMS RAFEHHRVDR NTVALTTPIA ELLIVAPEKL AEVGEFDPSK ERLLEYSRRC FLALDDETLK KVQALKKSKL LLPITYRFKR
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