About DNA-binding protein REPIN1
DNA-binding protein REPIN1 (REPIN1) is a protein
from Homo sapiens identified by UniProt accession
Q9BWE0, 567 residues long.
MolForge cross-references it against 0 known binders and
39 disease associations.
Target properties
| Protein name | DNA-binding protein REPIN1 |
|---|
| UniProt accession | Q9BWE0 |
|---|
| Gene | REPIN1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 567 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (39)
Diseases linked to this target (Open Targets).
- chemerin measurement · score 0.24
- platelet count · score 0.23
- systolic blood pressure · score 0.18
- protein measurement · score 0.18
- musculoskeletal system disease · score 0.12
- retinoic acid receptor responder protein 2 measurement · score 0.08
- Osteoporosis · score 0.07
- osteoporosis · score 0.07
- rotator cuff tear · score 0.06
- visual perception measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BWE0-F1 | alphafold | PREDICTED | 69.78 | — |
Amino-acid sequence (567 residues)
MLERRCRGPL AMGLAQPRLL SGPSQESPQT LGKESRGLRQ QGTSVAQSGA QAPGRAHRCA HCRRHFPGWV ALWLHTRRCQ ARLPLPCPEC GRRFRHAPFL ALHRQVHAAA TPDLGFACHL CGQSFRGWVA LVLHLRAHSA AKRPIACPKC ERRFWRRKQL RAHLRRCHPP APEARPFICG NCGRSFAQWD QLVAHKRVHV AEALEEAAAK ALGPRPRGRP AVTAPRPGGD AVDRPFQCAC CGKRFRHKPN LIAHRRVHTG ERPHQCPECG KRFTNKPYLT SHRRIHTGEK PYPCKECGRR FRHKPNLLSH SKIHKRSEGS AQAAPGPGSP QLPAGPQESA AEPTPAVPLK PAQEPPPGAP PEHPQDPIEA PPSLYSCDDC GRSFRLERFL RAHQRQHTGE RPFTCAECGK NFGKKTHLVA HSRVHSGERP FACEECGRRF SQGSHLAAHR RDHAPDRPFV CPDCGKAFRH KPYLAAHRRI HTGEKPYVCP DCGKAFSQKS NLVSHRRIHT GERPYACPDC DRSFSQKSNL ITHRKSHIRD GAFCCAICGQ TFDDEERLLA HQKKHDV
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