About Single-stranded DNA-binding protein 4
Single-stranded DNA-binding protein 4 (SSBP4) is a protein
from Homo sapiens identified by UniProt accession
Q9BWG4, 385 residues long.
MolForge cross-references it against 0 known binders and
53 disease associations.
Target properties
| Protein name | Single-stranded DNA-binding protein 4 |
| UniProt accession | Q9BWG4 |
| Gene | SSBP4 |
| Organism | Homo sapiens |
| Length | 385 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (53)
Diseases linked to this target (Open Targets).
- serum albumin measurement · score 0.17
- Red cell distribution width · score 0.17
- monocyte count · score 0.16
- basophil count · score 0.15
- body height · score 0.14
- basophil percentage of leukocytes · score 0.12
- HbA1c measurement · score 0.11
- systemic lupus erythematosus · score 0.09
- mean corpuscular hemoglobin concentration · score 0.09
- breast carcinoma · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q9BWG4-F1 | alphafold | PREDICTED | 53.64 | — |
Amino-acid sequence (385 residues)
MYAKGGKGSA VPSDSQAREK LALYVYEYLL HIGAQKSAQT FLSEIRWEKN ITLGEPPGFL HSWWCVFWDL YCAAPDRREA CEHSGEAKAF QDYSAAAAPS PVMGSMAPGD TMAAGSMAAG FFQGPPGSQP SPHNPNAPMM GPHGQPFMSP RFPGGPRPTL RMPSQPPAGL PGSQPLLPGA MEPSPRAQGH PSMGGPMQRV TPPRGMASVG PQSYGGGMRP PPNSLAGPGL PAMNMGPGVR GPWASPSGNS IPYSSSSPGS YTGPPGGGGP PGTPIMPSPG DSTNSSENMY TIMNPIGQGA GRANFPLGPG PEGPMAAMSA MEPHHVNGSL GSGDMDGLPK SSPGAVAGLS NAPGTPRDDG EMAAAGTFLH PFPSESYSPG MTMSV
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