Single-stranded DNA-binding protein 4 (SSBP4)

Homo sapiens — UniProt Q9BWG4

Gene: SSBP4Homo sapiensSwissProt reviewed

About Single-stranded DNA-binding protein 4

Single-stranded DNA-binding protein 4 (SSBP4) is a protein from Homo sapiens identified by UniProt accession Q9BWG4, 385 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.

Target properties

Protein nameSingle-stranded DNA-binding protein 4
UniProt accessionQ9BWG4
GeneSSBP4
OrganismHomo sapiens
Length385 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (53)

Diseases linked to this target (Open Targets).

  • serum albumin measurement · score 0.17
  • Red cell distribution width · score 0.17
  • monocyte count · score 0.16
  • basophil count · score 0.15
  • body height · score 0.14
  • basophil percentage of leukocytes · score 0.12
  • HbA1c measurement · score 0.11
  • systemic lupus erythematosus · score 0.09
  • mean corpuscular hemoglobin concentration · score 0.09
  • breast carcinoma · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BWG4-F1alphafoldPREDICTED53.64—

Amino-acid sequence (385 residues)

MYAKGGKGSA VPSDSQAREK LALYVYEYLL HIGAQKSAQT FLSEIRWEKN ITLGEPPGFL HSWWCVFWDL YCAAPDRREA CEHSGEAKAF QDYSAAAAPS PVMGSMAPGD TMAAGSMAAG FFQGPPGSQP SPHNPNAPMM GPHGQPFMSP RFPGGPRPTL RMPSQPPAGL PGSQPLLPGA MEPSPRAQGH PSMGGPMQRV TPPRGMASVG PQSYGGGMRP PPNSLAGPGL PAMNMGPGVR GPWASPSGNS IPYSSSSPGS YTGPPGGGGP PGTPIMPSPG DSTNSSENMY TIMNPIGQGA GRANFPLGPG PEGPMAAMSA MEPHHVNGSL GSGDMDGLPK SSPGAVAGLS NAPGTPRDDG EMAAAGTFLH PFPSESYSPG MTMSV

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Quick facts

UniProtQ9BWG4
GeneSSBP4
OrganismHomo sapiens
Length385
Binders0
Diseases53
View on UniProt