FUN14 domain-containing protein 2 (FUNDC2)

Homo sapiens — UniProt Q9BWH2

Gene: FUNDC2Homo sapiensSwissProt reviewed

About FUN14 domain-containing protein 2

FUN14 domain-containing protein 2 (FUNDC2) is a protein from Homo sapiens identified by UniProt accession Q9BWH2, 189 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.

Target properties

Protein nameFUN14 domain-containing protein 2
UniProt accessionQ9BWH2
GeneFUNDC2
OrganismHomo sapiens
Length189 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BWH2-F1alphafoldPREDICTED65.94—

Amino-acid sequence (189 residues)

METSAPRAGS QVVATTARHS AAYRADPLRV SSRDKLTEMA ASSQGNFEGN FESLDLAEFA KKQPWWRKLF GQESGPSAEK YSVATQLFIG GVTGWCTGFI FQKVGKLAAT AVGGGFFLLQ LANHTGYIKV DWQRVEKDMK KAKEQLKIRK SNQIPTEVRS KAEEVVSFVK KNVLVTGGFF GGFLLGMAS

Explore FUN14 domain-containing protein 2 with MolForge

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Quick facts

UniProtQ9BWH2
GeneFUNDC2
OrganismHomo sapiens
Length189
Binders0
Diseases47
View on UniProt