About Lipid transport auxiliary protein 1
Lipid transport auxiliary protein 1 (LTAP1) is a protein
from Homo sapiens identified by UniProt accession
Q9BWL3, 253 residues long.
MolForge cross-references it against 0 known binders and
34 disease associations.
Target properties
| Protein name | Lipid transport auxiliary protein 1 |
|---|
| UniProt accession | Q9BWL3 |
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| Gene | LTAP1 |
|---|
| Organism | Homo sapiens |
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| Length | 253 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (34)
Diseases linked to this target (Open Targets).
- mean corpuscular hemoglobin · score 0.09
- lung adenocarcinoma · score 0.07
- platelet count · score 0.05
- leukocyte count · score 0.05
- Combined hyperlipidemia · score 0.04
- cholesterol-ester transfer protein deficiency · score 0.04
- hypertriglyceridemia 2 · score 0.04
- pentosuria · score 0.04
- erythrocyte count · score 0.04
- serum gamma-glutamyl transferase measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BWL3-F1 | alphafold | PREDICTED | 73.12 | — |
Amino-acid sequence (253 residues)
MASGSNWLSG VNVVLVMAYG SLVFVLLFIF VKRQIMRFAM KSRRGPHVPV GHNAPKDLKE EIDIRLSRVQ DIKYEPQLLA DDDARLLQLE TQGNQSCYNY LYRMKALDAI RTSEIPFHSE GRHPRSLMGK NFRSYLLDLR NTSTPFKGVR KALIDTLLDG YETARYGTGV FGQNEYLRYQ EALSELATAV KARIGSSQRH HQSAAKDLTQ SPEVSPTTIQ VTYLPSSQKS KRAKHFLELK SFKDNYNTLE STL
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