About Proline-rich protein 14
Proline-rich protein 14 (PRR14) is a protein
from Homo sapiens identified by UniProt accession
Q9BWN1, 585 residues long.
MolForge cross-references it against 0 known binders and
32 disease associations.
Target properties
| Protein name | Proline-rich protein 14 |
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| UniProt accession | Q9BWN1 |
|---|
| Gene | PRR14 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 585 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
|---|
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BWN1-F1 | alphafold | PREDICTED | 55.15 | — |
Amino-acid sequence (585 residues)
MDLPGDSSPP GQPRLCRQPL TRALWGARSP KRPRLQLPGA PSPLEKASRR VLAVVLEDVM AVHMVPVVPS KQTSIPQHHS YHQDPVHRQP PASPPRQAGW SSQARPPDPL CLCREPLSRI HRTSSTLRRR SRTTPGPEEG PSQKVDRAPQ PTLVVMLEDI ASPRPPAEGF IDETPNFIIP AQRAEPMRIV RQPTPPPGDL EPPFQPSALP ADPLESPPTA PDPALELPST PPPSSLLRPR LSPWGLAPLF RSVRSKLESF ADIFLTPNKT PQPPPPSPPM KLELKIAISE AEQSGAAEGT ASVSPRPPIR QWRTQDHNTP ALLPKPSLGR SYSCPDLGPP GPGTCTWPPA PPQPSRPRPR RHTVGGGEMA RAPPPPRPCL RKEVFPLGGV GASPSLTTSC SSTASTSFSE PAEPRLGSTK GKEPRASKDQ VLSEPETKTM GKVSRFRIRR TPARPQLNLT PMGLPRPIRL NKKEFSLEEI YTNKNYQSPT TRRTFETIFE EPRERNGTLI FTSSRKLRRA VEFRDSSLPR SRRPSRGVRA AGGRTVPPNV APSPDVGPLL QQRLEELDAL LLEEETVDRE QPHWT
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