About Collectin-11
Collectin-11 (COLEC11) is a protein
from Homo sapiens identified by UniProt accession
Q9BWP8, 271 residues long.
MolForge cross-references it against 0 known binders and
106 disease associations.
Target properties
| Protein name | Collectin-11 |
|---|
| UniProt accession | Q9BWP8 |
|---|
| Gene | COLEC11 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 271 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (106)
Diseases linked to this target (Open Targets).
- 3MC syndrome 2 · score 0.78
- 3MC syndrome · score 0.61
- blood protein measurement · score 0.41
- low density lipoprotein cholesterol measurement · score 0.41
- genetic disorder · score 0.41
- high density lipoprotein cholesterol measurement · score 0.40
- triglyceride measurement · score 0.40
- alkaline phosphatase measurement · score 0.39
- total cholesterol measurement · score 0.39
- serum gamma-glutamyl transferase measurement · score 0.35
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BWP8-F1 | alphafold | PREDICTED | 78.28 | — |
Amino-acid sequence (271 residues)
MRGNLALVGV LISLAFLSLL PSGHPQPAGD DACSVQILVP GLKGDAGEKG DKGAPGRPGR VGPTGEKGDM GDKGQKGSVG RHGKIGPIGS KGEKGDSGDI GPPGPNGEPG LPCECSQLRK AIGEMDNQVS QLTSELKFIK NAVAGVRETE SKIYLLVKEE KRYADAQLSC QGRGGTLSMP KDEAANGLMA AYLAQAGLAR VFIGINDLEK EGAFVYSDHS PMRTFNKWRS GEPNNAYDEE DCVEMVASGG WNDVACHTTM YFMCEFDKEN M
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