Chitinase domain-containing protein 1 (CHID1)

About Chitinase domain-containing protein 1

Chitinase domain-containing protein 1 (CHID1) is a protein from Homo sapiens identified by UniProt accession Q9BWS9, 393 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.

Target properties

Protein name	Chitinase domain-containing protein 1
UniProt accession	Q9BWS9
Gene	CHID1
Organism	Homo sapiens
Length	393 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (24)

Diseases linked to this target (Open Targets).

body height · score 0.17
body mass index · score 0.15
glioblastoma multiforme · score 0.14
esophageal cancer · score 0.12
reticulocyte count · score 0.09
systolic blood pressure · score 0.09
neoplasm · score 0.07
non-small cell lung carcinoma · score 0.04
body fat percentage · score 0.02
body weight · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BWS9-F1	alphafold	PREDICTED	91.33	—

Amino-acid sequence (393 residues)

MRTLFNLLWL ALACSPVHTT LSKSDAKKAA SKTLLEKSQF SDKPVQDRGL VVTDLKAESV VLEHRSYCSA KARDRHFAGD VLGYVTPWNS HGYDVTKVFG SKFTQISPVW LQLKRRGREM FEVTGLHDVD QGWMRAVRKH AKGLHIVPRL LFEDWTYDDF RNVLDSEDEI EELSKTVVQV AKNQHFDGFV VEVWNQLLSQ KRVGLIHMLT HLAEALHQAR LLALLVIPPA ITPGTDQLGM FTHKEFEQLA PVLDGFSLMT YDYSTAHQPG PNAPLSWVRA CVQVLDPKSK WRSKILLGLN FYGMDYATSK DAREPVVGAR YIQTLKDHRP RMVWDSQASE HFFEYKKSRS GRHVVFYPTL KSLQVRLELA RELGVGVSIW ELGQGLDYFY DLL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards