Cell division cycle-associated protein 7 (CDCA7)

About Cell division cycle-associated protein 7

Cell division cycle-associated protein 7 (CDCA7) is a protein from Homo sapiens identified by UniProt accession Q9BWT1, 371 residues long. MolForge cross-references it against 0 known binders and 124 disease associations.

Target properties

Protein name	Cell division cycle-associated protein 7
UniProt accession	Q9BWT1
Gene	CDCA7
Organism	Homo sapiens
Length	371 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (124)

Diseases linked to this target (Open Targets).

ICF syndrome · score 0.73
Abnormal intestine morphology · score 0.46
immunodeficiency-centromeric instability-facial anomalies syndrome · score 0.46
Recurrent respiratory infections · score 0.46
mean corpuscular hemoglobin · score 0.41
mean corpuscular volume · score 0.41
breast carcinoma · score 0.39
self reported educational attainment · score 0.38
prostate carcinoma · score 0.38
mean reticulocyte volume · score 0.37

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BWT1-F1	alphafold	PREDICTED	68.77	—

Amino-acid sequence (371 residues)

MDARRVPQKD LRVKKNLKKF RYVKLISMET SSSSDDSCDS FASDNFANTR LQSVREGCRT RSQCRHSGPL RVAMKFPARS TRGATNKKAE SRQPSENSVT DSNSDSEDES GMNFLEKRAL NIKQNKAMLA KLMSELESFP GSFRGRHPLP GSDSQSRRPR RRTFPGVASR RNPERRARPL TRSRSRILGS LDALPMEEEE EEDKYMLVRK RKTVDGYMNE DDLPRSRRSR SSVTLPHIIR PVEEITEEEL ENVCSNSREK IYNRSLGSTC HQCRQKTIDT KTNCRNPDCW GVRGQFCGPC LRNRYGEEVR DALLDPNWHC PPCRGICNCS FCRQRDGRCA TGVLVYLAKY HGFGNVHAYL KSLKQEFEMQ A

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards