Meiotic nuclear division protein 1 homolog (MND1)

About Meiotic nuclear division protein 1 homolog

Meiotic nuclear division protein 1 homolog (MND1) is a protein from Homo sapiens identified by UniProt accession Q9BWT6, 205 residues long. MolForge cross-references it against 0 known binders and 120 disease associations.

Target properties

Protein name	Meiotic nuclear division protein 1 homolog
UniProt accession	Q9BWT6
Gene	MND1
Organism	Homo sapiens
Length	205 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (120)

Diseases linked to this target (Open Targets).

cortical surface area measurement · score 0.40
head and neck squamous cell carcinoma · score 0.23
breast adenocarcinoma · score 0.22
lung adenocarcinoma · score 0.21
total cholesterol measurement · score 0.13
alkaline phosphatase measurement · score 0.13
apolipoprotein A 1 measurement · score 0.13
serum albumin measurement · score 0.13
sex hormone-binding globulin measurement · score 0.12
C-reactive protein measurement · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BWT6-F1	alphafold	PREDICTED	91.07	—

Amino-acid sequence (205 residues)

MSKKKGLSAE EKRTRMMEIF SETKDVFQLK DLEKIAPKEK GITAMSVKEV LQSLVDDGMV DCERIGTSNY YWAFPSKALH ARKHKLEVLE SQLSEGSQKH ASLQKSIEKA KIGRCETEER TRLAKELSSL RDQREQLKAE VEKYKDCDPQ VVEEIRQANK VAKEAANRWT DNIFAIKSWA KRKFGFEENK IDRTFGIPED FDYID

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards