About Kanadaptin
Kanadaptin (SLC4A1AP) is a protein
from Homo sapiens identified by UniProt accession
Q9BWU0, 742 residues long.
MolForge cross-references it against 0 known binders and
29 disease associations.
Target properties
| Protein name | Kanadaptin |
|---|
| UniProt accession | Q9BWU0 |
|---|
| Gene | SLC4A1AP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 742 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (29)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- systolic blood pressure · score 0.20
- spinal stenosis · score 0.09
- alcohol consumption measurement · score 0.09
- drug use measurement · score 0.06
- erythrocyte count · score 0.05
- hematocrit · score 0.05
- lean body mass · score 0.05
- whole body water mass · score 0.05
- oral cavity cancer · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BWU0-F1 | alphafold | PREDICTED | 64.10 | — |
Amino-acid sequence (742 residues)
MADILSQSET LASQDLSGDF KKPALPVSPA ARSKAPASSS SNPEEVQKEG PTALQDSNSG EPDIPPPQPD CGDFRSLQEE QSRPPTAVSS PGGPARAPPY QEPPWGGPAT APYSLETLKG GTILGTRSLK GTSYCLFGRL SGCDVCLEHP SVSRYHAVLQ HRASGPDGEC DSNGPGFYLY DLGSTHGTFL NKTRIPPRTY CRVHVGHVVR FGGSTRLFIL QGPEEDREAE SELTVTQLKE LRKQQQILLE KKMLGEDSDE EEEMDTSERK INAGSQDDEM GCTWGMGEDA VEDDAEENPI VLEFQQEREA FYIKDPKKAL QGFFDREGEE LEYEFDEQGH STWLCRVRLP VDDSTGKQLV AEAIHSGKKK EAMIQCSLEA CRILDTLGLL RQEAVSRKRK AKNWEDEDFY DSDDDTFLDR TGLIEKKRLN RMKKAGKIDE KPETFESLVA KLNDAERELS EISERLKASS QVLSESPSQD SLDAFMSEMK SGSTLDGVSR KKLHLRTFEL RKEQQRLKGL IKIVKPAEIP ELKKTETQTT GAENKAKKLT LPLFGAMKGG SKFKLKTGTV GKLPPKRPEL PPTLMRMKDE PEVEEEEEEE EEEEKEKEEH EKKKLEDGSL SRPQPEIEPE AAVQEMRPPT DLTHFKETQT HENMSQLSEE EQNKDYQDCS KTTSLCAGPS ASKNEYEKSR GELKKKKTPG PGKLPPTLSS KYPEDDPDYC VWVPPEGQSG DGRTHLNDKY GY
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