About Spermatogenesis-associated protein 9
Spermatogenesis-associated protein 9 (SPATA9) is a protein
from Homo sapiens identified by UniProt accession
Q9BWV2, 254 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | Spermatogenesis-associated protein 9 |
|---|
| UniProt accession | Q9BWV2 |
|---|
| Gene | SPATA9 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 254 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (12)
Diseases linked to this target (Open Targets).
- FEV/FVC ratio · score 0.38
- chronic obstructive pulmonary disease · score 0.25
- pulmonary function measurement · score 0.24
- metabolite measurement · score 0.10
- drug use measurement · score 0.02
- papillary thyroid carcinoma · score 0.01
- Abnormal sperm morphology · score 0.01
- neoplasm · score 0.00
- male infertility · score 0.00
- non-alcoholic fatty liver disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BWV2-F1 | alphafold | PREDICTED | 58.11 | — |
Amino-acid sequence (254 residues)
MPIKPVGWIC GQVLKNFSGR IEGIQKAIMD LVDEFKDEFP TILRLSQSNQ KREPAQKTSK IRMAIALAKI NRATLIRGLN SISRSSKSVA KLLHPQLACR LLELRDISGR LLREVNAPRQ PLYNIQVRKG SLFEIISFPA KTALTSIIYA SYAALIYLAV CVNAVLKKVK NIFQEEESIR QNREESENCR KAFSEPVLSE PMFAEGEIKA KPYRSLPEKP DISDYPKLLA NKQSNNIQVL HSVFDQSAEM NEQI
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