About Cytidine and dCMP deaminase domain-containing protein 1
Cytidine and dCMP deaminase domain-containing protein 1 (CDADC1) is a protein
from Homo sapiens identified by UniProt accession
Q9BWV3, 514 residues long.
MolForge cross-references it against 0 known binders and
20 disease associations.
Target properties
| Protein name | Cytidine and dCMP deaminase domain-containing protein 1 |
|---|
| UniProt accession | Q9BWV3 |
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| Gene | CDADC1 |
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| Organism | Homo sapiens |
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| Length | 514 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (20)
Diseases linked to this target (Open Targets).
- vital capacity · score 0.29
- drug use measurement · score 0.11
- PR interval · score 0.11
- IGF-1 measurement · score 0.08
- Parkinson disease · score 0.03
- exanthem · score 0.03
- alcohol consumption measurement · score 0.02
- cystatin C measurement · score 0.02
- hypothyroidism · score 0.02
- COVID-19 · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BWV3-F1 | alphafold | PREDICTED | 79.59 | — |
Amino-acid sequence (514 residues)
MKEAGQMQNL ESARAGRSVS TQTGSMTGQI PRLSKVNLFT LLSLWMELFP AEAQRQKSQK NEEGKHGPLG DNEERTRVST DKRQVKRTGL VVVKNMKIVG LHCSSEDLHA GQIALIKHGS RLKNCDLYFS RKPCSACLKM IVNAGVNRIS YWPADPEISL LTEASSSEDA KLDAKAVERL KSNSRAHVCV LLQPLVCYMV QFVEETSYKC DFIQKITKTL PDANTDFYYE CKQERIKEYE MLFLVSNEEM HKQILMTIGL ENLCENPYFS NLRQNMKDLI LLLATVASSV PNFKHFGFYR SNPEQINEIH NQSLPQEIAR HCMVQARLLA YRTEDHKTGV GAVIWAEGKS RSCDGTGAMY FVGCGYNAFP VGSEYADFPH MDDKQKDREI RKFRYIIHAE QNALTFRCQE IKPEERSMIF VTKCPCDECV PLIKGAGIKQ IYAGDVDVGK KKADISYMRF GELEGVSKFT WQLNPSGAYG LEQNEPERRE NGVLRPVPQK EEQHQDKKLR LGIH
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