Single-stranded DNA-binding protein 3 (SSBP3)

About Single-stranded DNA-binding protein 3

Single-stranded DNA-binding protein 3 (SSBP3) is a protein from Homo sapiens identified by UniProt accession Q9BWW4, 388 residues long. MolForge cross-references it against 0 known binders and 82 disease associations.

Target properties

Protein name	Single-stranded DNA-binding protein 3
UniProt accession	Q9BWW4
Gene	SSBP3
Organism	Homo sapiens
Length	388 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (82)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.49
neuroimaging measurement · score 0.30
triglyceride measurement · score 0.30
blood urea nitrogen measurement · score 0.29
brain volume measurement · score 0.28
cortical surface area measurement · score 0.28
platelet count · score 0.27
electrocardiography · score 0.27
platelet component distribution width · score 0.27
body weight · score 0.26

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BWW4-F1	alphafold	PREDICTED	54.36	—

Amino-acid sequence (388 residues)

MFAKGKGSAV PSDGQAREKL ALYVYEYLLH VGAQKSAQTF LSEIRWEKNI TLGEPPGFLH SWWCVFWDLY CAAPERRDTC EHSSEAKAFH DYSAAAAPSP VLGNIPPNDG MPGGPIPPGF FQGPPGSQPS PHAQPPPHNP SSMMGPHSQP FMSPRYAGGP RPPIRMGNQP PGGVPGTQPL LPNSMDPTRQ QGHPNMGGSM QRMNPPRGMG PMGPGPQNYG SGMRPPPNSL GPAMPGINMG PGAGRPWPNP NSANSIPYSS SSPGTYVGPP GGGGPPGTPI MPSPADSTNS SDNIYTMINP VPPGGSRSNF PMGPGSDGPM GGMGGMEPHH MNGSLGSGDI DGLPKNSPNN ISGISNPPGT PRDDGELGGN FLHSFQNDNY SPSMTMSV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards