Tapasin-related protein (TAPBPL)

About Tapasin-related protein

Tapasin-related protein (TAPBPL) is a protein from Homo sapiens identified by UniProt accession Q9BX59, 468 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.

Target properties

Protein name	Tapasin-related protein
UniProt accession	Q9BX59
Gene	TAPBPL
Organism	Homo sapiens
Length	468 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (37)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.21
body height · score 0.14
Back pain · score 0.09
neoplasm · score 0.05
cortical surface area measurement · score 0.05
neurofibrillary tangles measurement · score 0.05
mean platelet volume · score 0.04
erythrocyte count · score 0.04
brain measurement · score 0.04
mean corpuscular volume · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BX59-F1	alphafold	PREDICTED	79.05	—

Amino-acid sequence (468 residues)

MGTQEGWCLL LCLALSGAAE TKPHPAEGQW RAVDVVLDCF LAKDGAHRGA LASSEDRARA SLVLKQVPVL DDGSLEDFTD FQGGTLAQDD PPIIFEASVD LVQIPQAEAL LHADCSGKEV TCEISRYFLQ MTETTVKTAA WFMANMQVSG GGPSISLVMK TPRVTKNEAL WHPTLNLPLS PQGTVRTAVE FQVMTQTQSL SFLLGSSASL DCGFSMAPGL DLISVEWRLQ HKGRGQLVYS WTAGQGQAVR KGATLEPAQL GMARDASLTL PGLTIQDEGT YICQITTSLY RAQQIIQLNI QASPKVRLSL ANEALLPTLI CDIAGYYPLD VVVTWTREEL GGSPAQVSGA SFSSLRQSVA GTYSISSSLT AEPGSAGATY TCQVTHISLE EPLGASTQVV PPERRTALGV IFASSLFLLA LMFLGLQRRQ APTGLGLLQA ERWETTSCAD TQSSHLHEDR TARVSQPS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards