About TM2 domain-containing protein 2
TM2 domain-containing protein 2 (TM2D2) is a protein
from Homo sapiens identified by UniProt accession
Q9BX73, 214 residues long.
MolForge cross-references it against 0 known binders and
24 disease associations.
Target properties
| Protein name | TM2 domain-containing protein 2 |
|---|
| UniProt accession | Q9BX73 |
|---|
| Gene | TM2D2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 214 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (24)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- cystatin C measurement · score 0.27
- BMI-adjusted waist circumference · score 0.22
- basophil count · score 0.18
- mean platelet volume · score 0.17
- body height · score 0.17
- leukocyte count · score 0.14
- myeloid white cell count · score 0.13
- red blood cell density measurement · score 0.11
- neutrophil count · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BX73-F1 | alphafold | PREDICTED | 80.41 | — |
Amino-acid sequence (214 residues)
MVLGGCPVSY LLLCGQAALL LGNLLLLHCV SRSHSQNATA EPELTSAGAA QPEGPGGAAS WEYGDPHSPV ILCSYLPDEF IECEDPVDHV GNATASQELG YGCLKFGGQA YSDVEHTSVQ CHALDGIECA SPRTFLRENK PCIKYTGHYF ITTLLYSFFL GCFGVDRFCL GHTGTAVGKL LTLGGLGIWW FVDLILLITG GLMPSDGSNW CTVY
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