About Rab11 family-interacting protein 5
Rab11 family-interacting protein 5 (RAB11FIP5) is a protein
from Homo sapiens identified by UniProt accession
Q9BXF6, 653 residues long.
MolForge cross-references it against 0 known binders and
33 disease associations.
Target properties
| Protein name | Rab11 family-interacting protein 5 |
| UniProt accession | Q9BXF6 |
| Gene | RAB11FIP5 |
| Organism | Homo sapiens |
| Length | 653 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (33)
Diseases linked to this target (Open Targets).
- urinary metabolite measurement · score 0.36
- cognitive function measurement · score 0.35
- self reported educational attainment · score 0.29
- intelligence · score 0.28
- glomerular filtration rate · score 0.27
- verbal-numerical reasoning measurement · score 0.25
- bone density · score 0.24
- schizophrenia · score 0.14
- alcohol consumption measurement · score 0.09
- drug use measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q9BXF6-F1 | alphafold | PREDICTED | 57.73 | — |
Amino-acid sequence (653 residues)
MALVRGAEPA AGPSRWLPTH VQVTVLRARG LRGKSSGAGS TSDAYTVIQV GREKYSTSVV EKTHGCPEWR EECSFELPPG ALDGLLRAQE ADAGPAPWAA SSAAACELVL TTMHRSLIGV DKFLGQATVA LDEVFGAGRA QHTQWYKLHS KPGKKEKERG EIEVTIQFTR NNLSASMFDL SMKDKPRSPF SKIRDKMKGK KKYDLESASA ILPSSAIEDP DLGSLGKMGK AKGFFLRNKL RKSSLTQSNT SLGSDSTLSS ASGSLAYQGP GAELLTRSPS RSSWLSTEGG RDSAQSPKLF THKRTYSDEA NQMRVAPPRA LLDLQGHLDA ASRSSLCVNG SHIYNEEPQG PVRHRSSISG SLPSSGSLQA VSSRFSEEGP RSTDDTWPRG SRSNSSSEAV LGQEELSAQA KVLAPGASHP GEEEGARLPE GKPVQVATPI VASSEAVAEK EGARKEERKP RMGLFHHHHQ GLSRSELGRR SSLGEKGGPI LGASPHHSSS GEEKAKSSWF GLREAKDPTQ KPSPHPVKPL SAAPVEGSPD RKQSRSSLSI ALSSGLEKLK TVTSGSIQPV TQAPQAGQMV DTKRLKDSAV LDQSAKYYHL THDELISLLL QRERELSQRD EHVQELESYI DRLLVRIMET SPTLLQIPPG PPK
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