About Cell division cycle-associated protein 4
Cell division cycle-associated protein 4 (CDCA4) is a protein
from Homo sapiens identified by UniProt accession
Q9BXL8, 241 residues long.
MolForge cross-references it against 0 known binders and
60 disease associations.
Target properties
| Protein name | Cell division cycle-associated protein 4 |
|---|
| UniProt accession | Q9BXL8 |
|---|
| Gene | CDCA4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 241 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (60)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.24
- body height · score 0.12
- t-tau measurement · score 0.10
- lung adenocarcinoma · score 0.10
- neoplasm · score 0.09
- cancer · score 0.08
- non-small cell lung carcinoma · score 0.08
- osteosarcoma · score 0.07
- hepatocellular carcinoma · score 0.07
- Miyoshi myopathy · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BXL8-F1 | alphafold | PREDICTED | 62.95 | — |
Amino-acid sequence (241 residues)
MFARGLKRKC VGHEEDVEGA LAGLKTVSSY SLQRQSLLDM SLVKLQLCHM LVEPNLCRSV LIANTVRQIQ EEMTQDGTWR TVAPQAAERA PLDRLVSTEI LCRAAWGQEG AHPAPGLGDG HTQGPVSDLC PVTSAQAPRH LQSSAWEMDG PRENRGSFHK SLDQIFETLE TKNPSCMEEL FSDVDSPYYD LDTVLTGMMG GARPGPCEGL EGLAPATPGP SSSCKSDLGE LDHVVEILVE T
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