FSD1-like protein (FSD1L)

About FSD1-like protein

FSD1-like protein (FSD1L) is a protein from Homo sapiens identified by UniProt accession Q9BXM9, 530 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.

Target properties

Protein name	FSD1-like protein
UniProt accession	Q9BXM9
Gene	FSD1L
Organism	Homo sapiens
Length	530 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (29)

Diseases linked to this target (Open Targets).

congenital hydrocephalus · score 0.34
neurodegenerative disease · score 0.26
cataract · score 0.16
smoking status measurement · score 0.04
alcohol consumption measurement · score 0.04
age at menarche · score 0.04
mathematical ability · score 0.03
high density lipoprotein cholesterol measurement · score 0.03
neurofibrillary tangles measurement · score 0.03
esophageal adenocarcinoma · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BXM9-F1	alphafold	PREDICTED	84.65	—

Amino-acid sequence (530 residues)

MDSQKYCFKE NENVTVDKAC FLISNITIGP ESINLQQEAL QRIISTLANK NDEIQNFIDT LHHTLKGVQE NSSNILSELD EEFDSLYSIL DEVKESMINC IKQEQARKSQ ELQSQISQCN NALENSEELL EFATRSLDIK EPEEFSKAAR QIKDRVTMAS AFRLSLKPKV SDNMTHLMVD FSQERQMLQT LKFLPVPKAP EIDPVECLVA DNSVTVAWRM PEEDNKIDHF ILEHRKTNFD GLPRVKDERC WEIIDNIKGT EYTLSGLKFD SKYMNFRVRA CNKAVAGEYS DPVTLETKAL NFNLDNSSSH LNLKVEDTCV EWDPTGGKGQ ESKIKGKENK GRSGTPSPKR TSVGSRPPAV RGSRDRFTGE SYTVLGDTAI ESGQHYWEVK AQKDCKSYSV GVAYKTLGKF DQLGKTNTSW CIHVNNWLQN TFAAKHNNKV KALDVTVPEK IGVFCDFDGG QLSFYDANSK QLLYSFKTKF TQPVLPGFMV WCGGLSLSTG MQVPSAVRTL QKSENGMTGS ASSLNNVVTQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards