About Calcyphosin-2
Calcyphosin-2 (CAPS2) is a protein
from Homo sapiens identified by UniProt accession
Q9BXY5, 538 residues long.
MolForge cross-references it against 0 known binders and
28 disease associations.
Target properties
| Protein name | Calcyphosin-2 |
|---|
| UniProt accession | Q9BXY5 |
|---|
| Gene | CAPS2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 538 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (28)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.28
- urate measurement · score 0.16
- bone density · score 0.16
- cup-to-disc ratio measurement · score 0.05
- intrathoracic organ injury · score 0.04
- goiter · score 0.02
- anxiety · score 0.02
- Autism · score 0.01
- major depressive disorder · score 0.01
- lung adenocarcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BXY5-F1 | alphafold | PREDICTED | 70.04 | — |
Amino-acid sequence (538 residues)
MDLEVKGVAA TSRSQIQPFF GRKKPLQQRW TSESWTNQNS CPPVVPRLDL GSLVDSDDED NFSYIPLSTA NLPNSSSTLG WVTPCQTPYT QYHLNKLDQN IIPENLPAPT DKCKLKYQQC KTEIKEGYKQ YSQRNAENTK SNVTHKQSPR NKIDEKCVQD EEANTDDLTT LDRKAILQQG YADNSCDKQQ RARKLDAEIV AAEKKKQIVA EQVMIDHLSR AVISDPEQNL AIEQKESDHI LPDSKMTPLR FRKRTLHETK IRTHSTLTEN VLSHKLQFDG RIVSRNGRDA CRELIGFFFT HDQSLTIYEY RQFGKNRTNV LPFIQKSIYS HQCGRRKGKQ YRLGDFYVGA TLTFLSSDHL SLPESIKENT LLKLRITNID QIALDSLKTA SMEQEDDIII QETNDRLVFK AIQDVLKEKL HKRGVRILTG LGKYFQQLDK EGNGLLDKAD FKQALKVFHL EVSEKDFESA WLILNDNGNG KVDYGEFKRG IIGEMNEYRK SYVRKAFMKL DFNKSGSVPI INIRKCYCAK KHSQVISG
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