Protein BEX2 (BEX2)

Homo sapiens — UniProt Q9BXY8

Gene: BEX2Homo sapiensSwissProt reviewed

About Protein BEX2

Protein BEX2 (BEX2) is a protein from Homo sapiens identified by UniProt accession Q9BXY8, 128 residues long. MolForge cross-references it against 0 known binders and 75 disease associations.

Target properties

Protein nameProtein BEX2
UniProt accessionQ9BXY8
GeneBEX2
OrganismHomo sapiens
Length128 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (75)

Diseases linked to this target (Open Targets).

  • hepatocellular carcinoma · score 0.07
  • retinitis pigmentosa · score 0.06
  • Familial exudative vitreoretinopathy · score 0.05
  • snowflake vitreoretinal degeneration · score 0.04
  • Familial ocular anterior segment mesenchymal dysgenesis · score 0.04
  • Familial drusen · score 0.04
  • Coats disease · score 0.04
  • exfoliation syndrome · score 0.04
  • Rare isolated myopia · score 0.04
  • birdshot chorioretinopathy · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BXY8-F1alphafoldPREDICTED68.48—

Amino-acid sequence (128 residues)

MESKEERALN NLIVENVNQE NDEKDEKEQV ANKGEPLALP LNVSEYCVPR GNRRRFRVRQ PILQYRWDIM HRLGEPQARM REENMERIGE EVRQLMEKLR EKQLSHSLRA VSTDPPHHDH HDEFCLMP

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Quick facts

UniProtQ9BXY8
GeneBEX2
OrganismHomo sapiens
Length128
Binders0
Diseases75
View on UniProt