About Protein BEX2
Protein BEX2 (BEX2) is a protein
from Homo sapiens identified by UniProt accession
Q9BXY8, 128 residues long.
MolForge cross-references it against 0 known binders and
75 disease associations.
Target properties
| Protein name | Protein BEX2 |
| UniProt accession | Q9BXY8 |
| Gene | BEX2 |
| Organism | Homo sapiens |
| Length | 128 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (75)
Diseases linked to this target (Open Targets).
- hepatocellular carcinoma · score 0.07
- retinitis pigmentosa · score 0.06
- Familial exudative vitreoretinopathy · score 0.05
- snowflake vitreoretinal degeneration · score 0.04
- Familial ocular anterior segment mesenchymal dysgenesis · score 0.04
- Familial drusen · score 0.04
- Coats disease · score 0.04
- exfoliation syndrome · score 0.04
- Rare isolated myopia · score 0.04
- birdshot chorioretinopathy · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q9BXY8-F1 | alphafold | PREDICTED | 68.48 | — |
Amino-acid sequence (128 residues)
MESKEERALN NLIVENVNQE NDEKDEKEQV ANKGEPLALP LNVSEYCVPR GNRRRFRVRQ PILQYRWDIM HRLGEPQARM REENMERIGE EVRQLMEKLR EKQLSHSLRA VSTDPPHHDH HDEFCLMP
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