Testis-expressed protein 101 (TEX101)

About Testis-expressed protein 101

Testis-expressed protein 101 (TEX101) is a protein from Homo sapiens identified by UniProt accession Q9BY14, 249 residues long. MolForge cross-references it against 0 known binders and 114 disease associations.

Target properties

Protein name	Testis-expressed protein 101
UniProt accession	Q9BY14
Gene	TEX101
Organism	Homo sapiens
Length	249 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (114)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.38
multiple sclerosis · score 0.12
Alzheimer disease · score 0.12
Parkinson disease · score 0.12
lysosomal storage disease · score 0.12
azoospermia · score 0.09
adolescent idiopathic scoliosis · score 0.08
male infertility with teratozoospermia due to single gene mutation · score 0.08
Rare genetic female infertility · score 0.07
Female infertility due to fertilization defect · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BY14-F1	alphafold	PREDICTED	81.55	—

Amino-acid sequence (249 residues)

MGTPRIQHLL ILLVLGASLL TSGLELYCQK GLSMTVEADP ANMFNWTTEE VETCDKGALC QETILIIKAG TETAILATKG CIPEGEEAIT IVQHSSPPGL IVTSYSNYCE DSFCNDKDSL SQFWEFSETT ASTVSTTLHC PTCVALGTCF SAPSLPCPNG TTRCYQGKLE ITGGGIESSV EVKGCTAMIG CRLMSGILAV GPMFVREACP HQLLTQPRKT ENGATCLPIP VWGLQLLLPL LLPSFIHFS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards