Inosine triphosphate pyrophosphatase (ITPA)

About Inosine triphosphate pyrophosphatase

Inosine triphosphate pyrophosphatase (ITPA) is a protein from Homo sapiens identified by UniProt accession Q9BY32, 194 residues long. MolForge cross-references it against 0 known binders and 111 disease associations.

Target properties

Protein name	Inosine triphosphate pyrophosphatase
UniProt accession	Q9BY32
Gene	ITPA
Organism	Homo sapiens
Length	194 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BY32-F1	alphafold	PREDICTED	95.05	—

Amino-acid sequence (194 residues)

MAASLVGKKI VFVTGNAKKL EEVVQILGDK FPCTLVAQKI DLPEYQGEPD EISIQKCQEA VRQVQGPVLV EDTCLCFNAL GGLPGPYIKW FLEKLKPEGL HQLLAGFEDK SAYALCTFAL STGDPSQPVR LFRGRTSGRI VAPRGCQDFG WDPCFQPDGY EQTYAEMPKA EKNAVSHRFR ALLELQEYFG SLAA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards