About Replication termination factor 2
Replication termination factor 2 (RTF2) is a protein
from Homo sapiens identified by UniProt accession
Q9BY42, 306 residues long.
MolForge cross-references it against 0 known binders and
27 disease associations.
Target properties
| Protein name | Replication termination factor 2 |
|---|
| UniProt accession | Q9BY42 |
|---|
| Gene | RTF2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 306 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (27)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.07
- reticulocyte count · score 0.05
- hair color · score 0.05
- hair shape measurement · score 0.05
- systolic blood pressure · score 0.05
- smoking status measurement · score 0.05
- balding measurement · score 0.04
- reticulocyte measurement · score 0.04
- hair colour measurement · score 0.04
- infection · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BY42-F1 | alphafold | PREDICTED | 72.30 | — |
Amino-acid sequence (306 residues)
MGCDGGTIPK RHELVKGPKK VEKVDKDAEL VAQWNYCTLS QEILRRPIVA CELGRLYNKD AVIEFLLDKS AEKALGKAAS HIKSIKNVTE LKLSDNPAWE GDKGNTKGDK HDDLQRARFI CPVVGLEMNG RHRFCFLRCC GCVFSERALK EIKAEVCHTC GAAFQEDDVI MLNGTKEDVD VLKTRMEERR LRAKLEKKTK KPKAAESVSK PDVSEEAPGP SKVKTGKPEE ASLDSREKKT NLAPKSTAMN ESSSGKAGKP PCGATKRSIA DSEESEAYKS LFTTHSSAKR SKEESAHWVT HTSYCF
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