Charged multivesicular body protein 4a (CHMP4A)

About Charged multivesicular body protein 4a

Charged multivesicular body protein 4a (CHMP4A) is a protein from Homo sapiens identified by UniProt accession Q9BY43, 222 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.

Target properties

Protein name	Charged multivesicular body protein 4a
UniProt accession	Q9BY43
Gene	CHMP4A
Organism	Homo sapiens
Length	222 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BY43-F1	alphafold	PREDICTED	79.15	—

Amino-acid sequence (222 residues)

MSGLGRLFGK GKKEKGPTPE EAIQKLKETE KILIKKQEFL EQKIQQELQT AKKYGTKNKR AALQALRRKK RFEQQLAQTD GTLSTLEFQR EAIENATTNA EVLRTMELAA QSMKKAYQDM DIDKVDELMT DITEQQEVAQ QISDAISRPM GFGDDVDEDE LLEELEELEQ EELAQELLNV GDKEEEPSVK LPSVPSTHLP AGPAPKVDED EEALKQLAEW VS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards