About Signal peptidase complex catalytic subunit SEC11C
Signal peptidase complex catalytic subunit SEC11C (SEC11C) is a protein
from Homo sapiens identified by UniProt accession
Q9BY50, 192 residues long.
MolForge cross-references it against 0 known binders and
25 disease associations.
Target properties
| Protein name | Signal peptidase complex catalytic subunit SEC11C |
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| UniProt accession | Q9BY50 |
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| Gene | SEC11C |
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| Organism | Homo sapiens |
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| Length | 192 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (25)
Diseases linked to this target (Open Targets).
- chronotype measurement · score 0.39
- endometrial cancer · score 0.26
- insomnia measurement · score 0.24
- circadian rhythm · score 0.18
- prostate carcinoma · score 0.16
- neurofibrillary tangles measurement · score 0.06
- PHF-tau measurement · score 0.06
- lung adenocarcinoma · score 0.05
- neoplasm · score 0.03
- protein measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BY50-F1 | alphafold | PREDICTED | 87.80 | — |
Amino-acid sequence (192 residues)
MVRAGAVGAH LPASGLDIFG DLKKMNKRQL YYQVLNFAMI VSSALMIWKG LIVLTGSESP IVVVLSGSME PAFHRGDLLF LTNFREDPIR AGEIVVFKVE GRDIPIVHRV IKVHEKDNGD IKFLTKGDNN EVDDRGLYKE GQNWLEKKDV VGRARGFLPY VGMVTIIMND YPKFKYALLA VMGAYVLLKR ES
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