Polymerase delta-interacting protein 3 (POLDIP3)

About Polymerase delta-interacting protein 3

Polymerase delta-interacting protein 3 (POLDIP3) is a protein from Homo sapiens identified by UniProt accession Q9BY77, 421 residues long. MolForge cross-references it against 0 known binders and 60 disease associations.

Target properties

Protein name	Polymerase delta-interacting protein 3
UniProt accession	Q9BY77
Gene	POLDIP3
Organism	Homo sapiens
Length	421 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BY77-F1	alphafold	PREDICTED	61.89	—

Amino-acid sequence (421 residues)

MADISLDELI RKRGAAAKGR LNARPGVGGV RSRVGIQQGL LSQSTRTATF QQRFDARQKI GLSDARLKLG VKDAREKLLQ KDARFRIKGK VQDAREMLNS RKQQTTVPQK PRQVADAREK ISLKRSSPAA FINPPIGTVT PALKLTKTIQ VPQQKAMAPL HPHPAGMRIN VVNNHQAKQN LYDLDEDDDG IASVPTKQMK FAASGGFLHH MAGLSSSKLS MSKALPLTKV VQNDAYTAPA LPSSIRTKAL TNMSRTLVNK EEPPKELPAA EPVLSPLEGT KMTVNNLHPR VTEEDIVELF CVCGALKRAR LVHPGVAEVV FVKKDDAITA YKKYNNRCLD GQPMKCNLHM NGNVITSDQP ILLRLSDSPS MKKESELPRR VNSASSSNPP AEVDPDTILK ALFKSSGASV TTQPTEFKIK L

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards