About Uncharacterized protein KIAA1671
Uncharacterized protein KIAA1671 (KIAA1671) is a protein
from Homo sapiens identified by UniProt accession
Q9BY89, 1806 residues long.
MolForge cross-references it against 0 known binders and
42 disease associations.
Target properties
| Protein name | Uncharacterized protein KIAA1671 |
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| UniProt accession | Q9BY89 |
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| Gene | KIAA1671 |
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| Organism | Homo sapiens |
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| Length | 1806 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (42)
Diseases linked to this target (Open Targets).
- lean body mass · score 0.28
- fat body mass · score 0.26
- sclerosing cholangitis · score 0.07
- age-related macular degeneration · score 0.07
- X-linked retinal dysplasia · score 0.06
- protein measurement · score 0.06
- hereditary motor and sensory neuropathy · score 0.06
- Familial exudative vitreoretinopathy · score 0.06
- retinitis pigmentosa · score 0.06
- severe early-childhood-onset retinal dystrophy · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BY89-F1 | alphafold | PREDICTED | 39.62 | — |
Amino-acid sequence (1806 residues)
MATRVEVGSI TPLTAVPGLG EMGKEETLTR TYFLQAGEAS GAPPARILEA KSPLRSPARL LPLPRLAPKP FSKEQDVKSP VPSLRPSSTG PSPSGGLSEE PAAKDLDNRM PGLVGQEVGS GEGPRTSSPL FNKAVFLRPS SSTMILFETT KSGPALGKAV SEGAEEAKLG VSGSRPEVAA KPALPTQKPA GTLPRSAPLS QDTKPPVPQE EAGQDHPPSK ASSVEDTARP LVEPRPRLKR RPVSAIFTES IQPQKPGPGA AATVGKVPPT PPEKTWVRKP RPLSMDLTAR FENKEALLRK VADEGSGPTA GDMAGLERPR AASKLDRDCL VKAEAPLHDP DLDFLEVAKK IRERKEKMLS KPEMGSPRAL VGGSSGVTPS NDQSPWEEKA KLDPEPEKAA ESPSPRLGRG LELAEVKSRV ADGEAAAGGE WASRRSVRKC ISLFREDSTL ALAVGSESPL ATPASPSAAP EPEKGVVSVQ ERIRGWTAES SEAKPEVRRR TFQARPLSAD LTKLFSSSAS SNEVKYEKSA ELSGEFPKEP REKQKEGHSL DGACIPRSPW KPGTLRDKSR QTEQKVSSNQ DPDSCRGGSS VEAPCPSDVT PEDDRSFQTV WATVFEHHVE RHTVADQSGR CLSTTPPGDM AHARVSEPRP RPEMGSWLGR DPPDMTKLKK ENSRGFDNPE TEKLGPTTLL NGELRPYHTP LRDKYPLSEN HNNNTFLKHL ENPPTSQRIE PRYDIVHAVG ERVHSEAISP APEEKAVTLR SLRSWLSLKD RQLSQEVTPA DLECGLEGQA GSVQRASLIW EARGMPEASG PKFGGNCPFP KWTGGAVVSS HKATVAVSEE HCAPGATSVR AIKAAIWESQ HEGPEGARSK PGVGARGPPQ GCPLDPLSRA TNGPSDSQAR THPDAFAVQK GPFIVAAREG DPGPAQVPQP AVRMRKAGAM DQRMDRWRRR TLPPNVKFDT FSSLVPEDSP HVGHRRTDYV SPTASALRKP QLSHYRVETQ EVNPGASRDQ TSPAVKQGSP VEPKATFFAV TYQIPNTQKA KGVVLSGAES LLEHSRKITP PSSPHSLTST LVSLGHEEAL EMAGSKNWMK GREHENASIL KTLKPTDRPS SLGAWSLDPF NGRIIDVDAL WSHRGSEDGP RPQSNWKESA NKMSPSGGAP QTTPTLRSRP KDLPVRRKTD VISDTFPGKI RDGYRSSVLD IDALMAEYQE LSLKVPGEAQ ERRSPTVEPS TLPRERPVQL GGVEQRRRSL KEMPDTGGLW KPASSAEINH SFTPGLGKQL AETLETAMGT KSSPPFWALP PSAPSERYPG GSPIPADPRK KTGFAEDDRK AFASKHHVAK CQNYLAESKP SGREDPGSGV RVSPKSPPTD QKKGTPRKST GRGEEDSVAQ WGDHPRDCGR VPLDIKRAYS EKGPPANIRE GLSIMHEARE RRREQPKGRP SLTGENLEAK MGPCWWESGT GDSHKVLPRD LEKEDAPQEK ERPLQQVSPV ASVPWRSHSF CKDRRSGPFV DQLKQCFSRQ PTEPKDTDTL VHEAGSQYGT WTEQCQSGES LATESPDSSA TSTRKQPPSS RLSSLSSQTE PTSAGDQYDC SRDQRSTSVD HSSTDLESTD GMEGPPPPDA CPEKRVDDFS FIDQTSVLDS SALKTRVQLS KRSRRRAPIS HSLRRSRFSE SESRSPLEDE TDNTWMFKDS TEEKSPRKEE SDEEETASKA ERTPVSHPQR MPAFPGMDPA VLKAQLHKRP EVDSPGETPS WAPQPKSPKS PFQPGVLGSR VLPSSMDKDE RSDEPSPQWL KELKSKKRQS LYENQV
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