About SH3 and multiple ankyrin repeat domains protein 3
SH3 and multiple ankyrin repeat domains protein 3 (SHANK3) is a protein
from Homo sapiens identified by UniProt accession
Q9BYB0, 1806 residues long.
MolForge cross-references it against 0 known binders and
0 disease associations.
Target properties
| Protein name | SH3 and multiple ankyrin repeat domains protein 3 |
|---|
| UniProt accession | Q9BYB0 |
|---|
| Gene | SHANK3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 1806 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BYB0-F1 | alphafold | PREDICTED | 52.42 | — |
Amino-acid sequence (1806 residues)
MQLSRAAAAA AAAPAEPPEP LSPAPAPAPA PPGPLPRSAA DGAPAGGKGG PGRRAESPGA PFPGASGPGP GPGAGMDGPG ASAVVVRVGI PDLQQTKCLR LDPAAPVWAA KQRVLCALNH SLQDALNYGL FQPPSRGRAG KFLDEERLLQ EYPPNLDTPL PYLEFRYKRR VYAQNLIDDK QFAKLHTKAN LKKFMDYVQL HSTDKVARLL DKGLDPNFHD PDSGECPLSL AAQLDNATDL LKVLKNGGAH LDFRTRDGLT AVHCATRQRN AAALTTLLDL GASPDYKDSR GLTPLYHSAL GGGDALCCEL LLHDHAQLGI TDENGWQEIH QACRFGHVQH LEHLLFYGAD MGAQNASGNT ALHICALYNQ ESCARVLLFR GANRDVRNYN SQTAFQVAII AGNFELAEVI KTHKDSDVVP FRETPSYAKR RRLAGPSGLA SPRPLQRSAS DINLKGEAQP AASPGPSLRS LPHQLLLQRL QEEKDRDRDA DQESNISGPL AGRAGQSKIS PSGPGGPGPA PGPGPAPPAP PAPPPRGPKR KLYSAVPGRK FIAVKAHSPQ GEGEIPLHRG EAVKVLSIGE GGFWEGTVKG RTGWFPADCV EEVQMRQHDT RPETREDRTK RLFRHYTVGS YDSLTSHSDY VIDDKVAVLQ KRDHEGFGFV LRGAKAETPI EEFTPTPAFP ALQYLESVDV EGVAWRAGLR TGDFLIEVNG VNVVKVGHKQ VVALIRQGGN RLVMKVVSVT RKPEEDGARR RAPPPPKRAP STTLTLRSKS MTAELEELAS IRRRKGEKLD EMLAAAAEPT LRPDIADADS RAATVKQRPT SRRITPAEIS SLFERQGLPG PEKLPGSLRK GIPRTKSVGE DEKLASLLEG RFPRSTSMQD PVREGRGIPP PPQTAPPPPP APYYFDSGPP PAFSPPPPPG RAYDTVRSSF KPGLEARLGA GAAGLYEPGA ALGPLPYPER QKRARSMIIL QDSAPESGDA PRPPPAATPP ERPKRRPRPP GPDSPYANLG AFSASLFAPS KPQRRKSPLV KQLQVEDAQE RAALAVGSPG PGGGSFAREP SPTHRGPRPG GLDYGAGDGP GLAFGGPGPA KDRRLEERRR STVFLSVGAI EGSAPGADLP SLQPSRSIDE RLLGTGPTAG RDLLLPSPVS ALKPLVSGPS LGPSGSTFIH PLTGKPLDPS SPLALALAAR ERALASQAPS RSPTPVHSPD ADRPGPLFVD VQARDPERGS LASPAFSPRS PAWIPVPARR EAEKVPREER KSPEDKKSMI LSVLDTSLQR PAGLIVVHAT SNGQEPSRLG GAEEERPGTP ELAPAPMQSA AVAEPLPSPR AQPPGGTPAD AGPGQGSSEE EPELVFAVNL PPAQLSSSDE ETREELARIG LVPPPEEFAN GVLLATPLAG PGPSPTTVPS PASGKPSSEP PPAPESAADS GVEEADTRSS SDPHLETTST ISTVSSMSTL SSESGELTDT HTSFADGHTF LLEKPPVPPK PKLKSPLGKG PVTFRDPLLK QSSDSELMAQ QHHAASAGLA SAAGPARPRY LFQRRSKLWG DPVESRGLPG PEDDKPTVIS ELSSRLQQLN KDTRSLGEEP VGGLGSLLDP AKKSPIAAAR LFSSLGELSS ISAQRSPGGP GGGASYSVRP SGRYPVARRA PSPVKPASLE RVEGLGAGAG GAGRPFGLTP PTILKSSSLS IPHEPKEVRF VVRSVSARSR SPSPSPLPSP ASGPGPGAPG PRRPFQQKPL QLWSKFDVGD WLESIHLGEH RDRFEDHEIE GAHLPALTKD DFVELGVTRV GHRMNIERAL RQLDGS
Explore SH3 and multiple ankyrin repeat domains protein 3 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets