About Large ribosomal subunit protein bL32m
Large ribosomal subunit protein bL32m (MRPL32) is a protein
from Homo sapiens identified by UniProt accession
Q9BYC8, 188 residues long.
MolForge cross-references it against 0 known binders and
24 disease associations.
Target properties
| Protein name | Large ribosomal subunit protein bL32m |
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| UniProt accession | Q9BYC8 |
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| Gene | MRPL32 |
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| Organism | Homo sapiens |
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| Length | 188 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (24)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- cortical surface area measurement · score 0.31
- neuroimaging measurement · score 0.30
- brain measurement · score 0.22
- cortical thickness · score 0.20
- BMI-adjusted waist-hip ratio · score 0.18
- BMI-adjusted waist circumference · score 0.17
- heel bone mineral density · score 0.16
- body fat percentage · score 0.16
- neurofibrillary tangles measurement · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BYC8-F1 | alphafold | PREDICTED | 76.84 | — |
Amino-acid sequence (188 residues)
MALAMLVLVV SPWSAARGVL RNYWERLLRK LPQSRPGFPS PPWGPALAVQ GPAMFTEPAN DTSGSKENSS LLDSIFWMAA PKNRRTIEVN RCRRRNPQKL IKVKNNIDVC PECGHLKQKH VLCAYCYEKV CKETAEIRRQ IGKQEGGPFK APTIETVVLY TGETPSEQDQ GKRIIERDRK RPSWFTQN
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