Large ribosomal subunit protein bL20m (MRPL20)

About Large ribosomal subunit protein bL20m

Large ribosomal subunit protein bL20m (MRPL20) is a protein from Homo sapiens identified by UniProt accession Q9BYC9, 149 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

Target properties

Protein name	Large ribosomal subunit protein bL20m
UniProt accession	Q9BYC9
Gene	MRPL20
Organism	Homo sapiens
Length	149 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (20)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.36
peak expiratory flow · score 0.08
myxedema · score 0.07
heel bone mineral density · score 0.07
osteoporosis · score 0.05
inflammatory bowel disease · score 0.05
body height · score 0.05
diastolic blood pressure · score 0.04
obstructive sleep apnea · score 0.03
ulcerative colitis · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BYC9-F1	alphafold	PREDICTED	90.98	—

Amino-acid sequence (149 residues)

MVFLTAQLWL RNRVTDRYFR IQEVLKHARH FRGRKNRCYR LAVRTVIRAF VKCTKARYLK KKNMRTLWIN RITAASQEHG LKYPALIGNL VKCQVELNRK VLADLAIYEP KTFKSLAALA SRRRHEGFAA ALGDGKEPEG IFSRVVQYH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards