Large ribosomal subunit protein uL13m (MRPL13)

About Large ribosomal subunit protein uL13m

Large ribosomal subunit protein uL13m (MRPL13) is a protein from Homo sapiens identified by UniProt accession Q9BYD1, 178 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.

Target properties

Protein name	Large ribosomal subunit protein uL13m
UniProt accession	Q9BYD1
Gene	MRPL13
Organism	Homo sapiens
Length	178 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (41)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.36
optic cup area measurement · score 0.23
breast cancer · score 0.10
neoplasm · score 0.09
cancer · score 0.09
lung adenocarcinoma · score 0.08
squamous cell carcinoma · score 0.07
body height · score 0.07
BMI-adjusted waist-hip ratio · score 0.07
pathological myopia · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BYD1-F1	alphafold	PREDICTED	93.19	—

Amino-acid sequence (178 residues)

MSSFSRAPQQ WATFARIWYL LDGKMQPPGK LAAMASIRLQ GLHKPVYHAL SDCGDHVVIM NTRHIAFSGN KWEQKVYSSH TGYPGGFRQV TAAQLHLRDP VAIVKLAIYG MLPKNLHRRT MMERLHLFPD EYIPEDILKN LVEELPQPRK IPKRLDEYTQ EEIDAFPRLW TPPEDYRL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards