Large ribosomal subunit protein uL4m (MRPL4)

About Large ribosomal subunit protein uL4m

Large ribosomal subunit protein uL4m (MRPL4) is a protein from Homo sapiens identified by UniProt accession Q9BYD3, 311 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.

Target properties

Protein name	Large ribosomal subunit protein uL4m
UniProt accession	Q9BYD3
Gene	MRPL4
Organism	Homo sapiens
Length	311 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (42)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.48
alkaline phosphatase measurement · score 0.18
FEV/FVC ratio · score 0.16
pulse pressure measurement · score 0.16
body height · score 0.14
reticulocyte measurement · score 0.06
reticulocyte count · score 0.05
monocyte percentage of leukocytes · score 0.05
fat body mass · score 0.05
lean body mass · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BYD3-F1	alphafold	PREDICTED	83.78	—

Amino-acid sequence (311 residues)

MLQFVRAGAR AWLRPTGSQG LSSLAEEAAR ATENPEQVAS EGLPEPVLRK VELPVPTHRR PVQAWVESLR GFEQERVGLA DLHPDVFATA PRLDILHQVA MWQKNFKRIS YAKTKTRAEV RGGGRKPWPQ KGTGRARHGS IRSPLWRGGG VAHGPRGPTS YYYMLPMKVR ALGLKVALTV KLAQDDLHIM DSLELPTGDP QYLTELAHYR RWGDSVLLVD LTHEEMPQSI VEATSRLKTF NLIPAVGLNV HSMLKHQTLV LTLPTVAFLE DKLLWQDSRY RPLYPFSLPY SDFPRPLPHA TQGPAATPYH C

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards