Late cornified envelope protein 3D (LCE3D)

About Late cornified envelope protein 3D

Late cornified envelope protein 3D (LCE3D) is a protein from Homo sapiens identified by UniProt accession Q9BYE3, 92 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.

Target properties

Protein name	Late cornified envelope protein 3D
UniProt accession	Q9BYE3
Gene	LCE3D
Organism	Homo sapiens
Length	92 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (34)

Diseases linked to this target (Open Targets).

breast adenocarcinoma · score 0.22
esophageal cancer · score 0.17
gastric adenocarcinoma · score 0.16
psoriasis · score 0.13
urinary bladder cancer · score 0.11
squamous cell lung carcinoma · score 0.11
endometrial cancer · score 0.10
type 2 diabetes mellitus · score 0.08
ankylosing spondylitis · score 0.07
sclerosing cholangitis · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BYE3-F1	alphafold	PREDICTED	59.76	—

Amino-acid sequence (92 residues)

MSCQQNQQQC QPPPKCPSPK CPPKSPVQCL PPASSGCAPS SGGCGPSSEG GCFLNHHRRH HRCRRQRPNS CDRGSGQQGG GSGCGHGSGG CC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards